To my shame I see it was nearly a year ago that I worked out the microphone and speaker connections on my TYT MD380 handheld - see the blog here:
Mic and speaker connections for TYT MD380
I have a home-made hands-free set up for operating mobile with my analogue handheld (an FT60E) and I would like to use something similar for the digital radio.
The microphone is a small electret condenser capsule, mounted on a microphone boom of galvanised iron wire (coat-hanger wire!) which is attached to a baseball hat. The microphone is quite close to the mouth, but not directly in front to avoid breath-blast. When I made my first version, I stitched the wire to the front of the cap, which was quite time consuming. The current one is glued to the back of the brim with hot-melt glue. Not very pretty, but quite quick to do.
The transmit switch is a toggle switch that is taped to the side of a cigarette-lighter plug that is located very conveniently beside the gear-change stick. This makes it very easy to flip between TX and RX without taking my eyes off the road. And also doesn't involve drilling any holes in car.
I use a Diamond dual-band mobile antenna on the motor car, mounted on the tailgate and connected to the radio via RG58, a BNC and one of those BNC - SMA adaptors.
Testing: I first checked the speaker connections, plugging the 2.5mm plug in and listening to the World-wide talk-group on the local repeater. When all was working on the receive side, I made sure the TX/RX switch was "off" and plugged in the 3.5mm jack. Now, on our local repeater GB7AS, we have a special Talk-group on Slot 2 which echos back the transmit audio after a short delay, for people to test their radios. This is called TG9990 Echo Test. If you don't have this, then you will have to get a friend to listen to your audio and check it is working well. you can see if the TX/RX switch is working because the LED on the top of the radio goes red in transmit. Have fun!